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Does CBD Pass Into Breast Milk? What Studies Reveal

Does CBD Pass Into Breast Milk? What Studies Reveal

Mar 15, 2025

Even though cannabinoids can enter breast milk, many breastfeeding mothers are unconcerned about using cannabis — is the same true for users of CBD, the non-intoxicating form of cannabis?

Science hasn’t yet revealed very much regarding the safety of using CBD while breastfeeding, but mothers who use CBD are generally much more responsible than cannabis users at large. You don’t want to get high — you just want what’s right for your baby.

Should you stop using CBD at all while breastfeeding? Can CBD make its way into breast milk, and can it then harm your baby? We’ll answer all these questions throughout the course of the guide, providing real data you can use to make responsible decisions.

What is CBD?

Cannabidiol (CBD) is a non-intoxicating cannabinoid naturally found in cannabis. While it’s mildly relaxing, CBD doesn’t produce anything close to a “high” — CBD lacks THC’s intoxicating attributes, and it’s generally considered safer to use than THC.

Also unlike THC, CBD is considered “industrial hemp” and is legal by federal law. Many mothers rely on CBD before they’re pregnant for help with sleeping or stress relief, and they naturally want to know whether it’s safe to start using CBD during the postpartum period.

Is CBD Safe While Breastfeeding?

The safety of using CBD while breastfeeding is unknown. CBD lacks many of the negative attributes of THC, but it still impacts the endocannabinoid and endocrine systems of you and your infant, potentially in negative ways.

In some cases, the benefits of using CBD while breastfeeding may outweigh the potential dangers. Always consult with your doctor before you start using CBD as a breastfeeding mother.

Why Some Breastfeeding Mothers Consider Using CBD

It’s natural to want to try using CBD while you’re breastfeeding. Some common reasons that postpartum mothers might want to use CBD include:

Postpartum pain: The process of your body recovering from having a baby is painful and uncomfortable. CBD is generally seen as a “side effect free” remedy for pain that’s safe and natural.
Stress & depression: CBD also often has a soothing effect on the mind. The postpartum period is fraught with unexpected stresses and strong waves of depression — both of which CBD is often seen as alleviating.
Help with sleep: Countless thousands of people have experienced relief using CBD gummies for sleep. With sleep so hard to come by during the postpartum period, CBD is an attractive solution.
Improving overall health: During normal times in life, it’s common to use CBD as a general health aid. Pregnancy is a delicate period, however, with its own rules regarding what’s healthy and what’s not.

CBD Breastfeeding Studies: Does CBD Pass Into Breast Milk?

According to the studies, yes, CBD does enter breast milk when you use it while breastfeeding. A 2024 research review confirmed that “cannabinoids are stored in adipose tissue, can easily reach the mammary gland, and can be secreted in milk.” Furthermore, it noted that “the endocannabinoid system is intimately connected to the endocrine system,” finding that “interactions of exogenous cannabinoids with the endocannabinoid system might modify release of critical hormones… that regulate milk production and secretion.”

So, not only does CBD enter your breast milk if you use the cannabinoid while breastfeeding, but it might also alter your ability to produce milk.

How Much CBD Passes Through?

Early research indicated that as little as 1% of the cannabinoids you use enter your breastmilk. By 2018, however, scientists began admitting that up to 8.7% of the cannabinoids you ingest can end up in your breast milk — though that’s with inhaled THC.

Overall, it might be reasonable to assume that around 5% of the CBD you use enters your breast milk. That means if you use 100mg CBD, your baby will end up ingesting around 5mg.

Potential Side Effects of Taking CBD While Nursing

Using CBD while breastfeeding could result in reduced breast milk production and developmental issues in your baby. However, we know very little about the types of side effects that might occur for both you and your baby if you use CBD while breastfeeding.

The vast majority of the research on this subject has concerned maternal marijuana use — in other words, THC cannabis consumption. THC is rightfully seen as the bigger threat since a startling number of mothers use THC cannabis. THC-rich cannabis products are almost unrecognizably different from CBD, however, making data comparisons difficult.

What we do know is that using recreational or medical marijuana during pregnancy and while breastfeeding has the potential to seriously harm your baby. The relative dangers of THC to adults aside, prenatal and postnatal exposure to an intoxicating substance is an entirely different matter. Any mothers struggling with substance use should seek community assistance immediately to avoid infant marijuana exposure.

What Do Health Authorities Say About CBD and Breastfeeding?

Every single major health authority strongly recommends against using CBD while breastfeeding. Whether it’s the FDA, the CDC, or the American Academy of Pediatrics (AAP), medical experts advise that the risks of using CBD while breastfeeding outweigh any potential benefits. It’s not that these authorities find CBD to be dangerous overall — it’s just that, in light of the evidence, exposing infants to cannabinoids of any kind does not appear to be a wise decision.

Does CBD Affect Breast Milk?

Yes, CBD does affect your breast milk — it may reduce your milk production, and it might alter the delicate hormones in breast milk that are vital to infant and toddler development. We don’t know exactly how CBD affects breast milk, and the impact is likely mild. When considering the health of your child, however, it can be prudent to avoid certain substances until your body is your own again.

Is CBD Harmful to Babies?

Yes, CBD might be harmful to babies even though it’s generally seen as safe for adults. We don’t know enough about CBD to be sure, but many substances that are usually safe are nonetheless dangerous during infancy — that’s why breastfeeding mothers usually abstain from alcohol, prescription medications, and even over-the-counter drugs like aspirin as well.

Unless the benefits of using CBD are compelling in your particular case, it’s best to avoid any potential harm to your baby by not using CBD. Different types of CBD affect your infant’s body in different ways, though:

CBD Oil and Breastfeeding

Internally ingested CBD products like CBD oil are what you want to avoid while breastfeeding. They pass from your digestive tract into your bloodstream where they’re deposited in fatty tissues like your breasts.

CBD Topicals and Breastfeeding

Interestingly, CBD topicals are generally fine to use while pregnant or breastfeeding. That’s because the CBD they contain doesn’t enter your bloodstream — it remains localized to the area where you applied it. So, just don’t apply your CBD topical to your breasts, and this is one way you can still use CBD while breastfeeding.

CBD Gummies and Breastfeeding

Since they’re internally ingested, CBD gummies are — unfortunately — not okay to use while breastfeeding. Even broad-spectrum CBD gummies still contain CBD despite the fact that THC is eliminated. It’s best to abstain until your little one is eating on his or her own.

Smoking CBD While Breastfeeding

Smoking or vaping CBD while breastfeeding has the greatest potential to harm your infant. Not only does doing so introduce CBD into your bloodstream, but it also releases cannabinoids into the air where your baby can inhale them. Even if you use other forms of CBD, at least avoid inhalable products while you’re breastfeeding.

Conclusion: Using CBD Postpartum

Even though cannabis use while pregnant and breastfeeding alarmingly doesn’t appear to be much of a concern to THC-using moms, we know CBD users are different. You want only what’s best for your baby, and you now know that the cannabis plant has no place near your developing fetus or infant — even if it’s the type of cannabis that doesn’t get you high.

As you start to get your bodily autonomy back, plan for how you’ll reincorporate CBD into your daily routine. You may also decide that CBD is no longer a danger to your baby at a certain point — just check in with your doctor to make sure this is an appropriate time to start using the cannabinoid again.

We know you want what’s best for your baby, and that — of course — includes doing what’s best for you as well. Temporary fixes like CBD can be tempting, but in the end, it’s best to stick with what you know is safe. Ask a doctor, and make your own decision — is using CBD while breastfeeding right for you, or is it best to wait until your body is fully your own once again?

Colorado Botanicals will be there to supply the world’s best CBD whenever you’re ready. Don’t be afraid to contact us for product recommendations and further tips for mothers who want to use CBD.

Sources

Castro-Navarro, I., McGuire, M. A., Williams, J. E., Holdsworth, E. A., Meehan, C. L., & McGuire, M. K. (2024). Maternal Cannabis Use during Lactation and Potential Effects on Human Milk Composition and Production: A Narrative Review. Advances in Nutrition, 15(4), 100196. https://doi.org/10.1016/j.advnut.2024.100196
Baker, T., Datta, P., Rewers-Felkins, K., Thompson, H., Kallem, R. R., & Hale, T. W. (2018). Transfer of inhaled cannabis into human breast milk. Obstetrics and Gynecology, 131(5), 783–788. https://doi.org/10.1097/aog.0000000000002575
Castro-Navarro, I., McGuire, M. A., Williams, J. E., Holdsworth, E. A., Meehan, C. L., & McGuire, M. K. (2024). Maternal Cannabis Use during Lactation and Potential Effects on Human Milk Composition and Production: A Narrative Review. Advances in Nutrition, 15(4), 100196. https://doi.org/10.1016/j.advnut.2024.100196

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March 12, 2025

How Long Do CBD Gummies Last? Effects & Duration

The effects of CBD gummies only last a few hours, but the CBD in those gummies can stick around in your body for up to 30 days after ingestion. Both for those who want their CBD gummies to last longer and for individuals facing drug testing, knowing exactly how long CBD gummies can last is naturally a priority. In this guide, you’ll find out why the effects of CBD gummies last as long as they do, and you’ll also discover the reasons the CBD in your gummies might stay in your body for up to a full month. By the end, you’ll be well-equipped to use CBD gummies safely and responsibly. How Long Do CBD Gummies Last in Your System? Even though the effects of CBD gummies dissipate within 3-5 hours, traces of the CBD they contain can remain in your digestive tract for up to 30 days, gradually excreting in your urine. When it comes to detecting cannabinoids in drug testing, though, it’s THC you have to worry about — drug tests don’t detect CBD. There are ways you can take CBD while avoiding THC, and it’s also just as possible to lengthen the effects of CBD gummies as it is to shorten them. Learn more below: How Long Do the Effects Last? The effects of CBD gummies generally last for 3-5 hours but can vary based on factors like: Dosage Metabolism Digestion CBD type Duration It generally takes your digestive tract at least 3 hours to stop CBD from entering your bloodstream. Taking CBD gummies on an empty stomach can make them kick in faster, and continuing to not eat afterward might make them last longer. The longest the effects of a single dose of CBD gummies will ever last is 6-7 hours, though. Timeline 0-30 minutes: Initial effects of CBD gummies start to kick in. Mild relaxation may be felt. 30-60 minutes: The primary effects of CBD gummies set in. Stronger feelings of relaxation. 60 minutes to 3 hours: The CBD in your gummies continues to exert strong effects. 3-6 hours: CBD gummies begin to wear off. 6+ hours: The effects of CBD gummies should no longer be noticeable. Why It Matters CBD is non-intoxicating, but that doesn’t mean it has no effect. Most experts recommend that you avoid operating heavy machinery or performing any other complex tasks while experiencing the primary effects of CBD. Also, understanding how these hemp edibles work in the body helps you determine a safe and effective CBD gummy dosage. Whether you’re taking 25mg CBD gummies or you’ve chosen any other dose, knowing when your gummies have worn off is the first step toward deciding when to take more. How Long Does CBD Stay in Your Body? The amount of time CBD stays in your body varies depending on a variety of factors: A single dose of CBD will usually only stay in the body for 1-3 days Repeated doses add up, however, causing the cannabinoid to stay in your body longer For daily CBD users, cannabinoids may still be present in tissue samples for up to 30 days after use Individual metabolism, the size of the CBD doses taken, and many other variables can also have an impact Detectability CBD and drug testing is certainly a relevant topic due to the potential for a false positive, but it isn’t CBD that drug tests are detecting. In fact, the types of urinalysis tests commonly used in workplaces and correctional institutions can’t detect CBD — they aren’t designed to detect this cannabinoid and are on the lookout for THC instead. Half-Life The amount of time it takes the CBD or THC in your system to decrease by half — known as half life — varies depending on the factors we’ve already discussed such as metabolism and dose. However, cannabinoids generally have a half life of around 24 hours — if you consume 100mg CBD, only around 50mg will remain in your body one day later. Drug Test Concerns At the levels it’s present in CBD products (less than 0.3%), the half life of THC shouldn’t be a concern for CBD users. Eating enough full-spectrum CBD gummies, however — which contain traces of THC — could eventually lead this illicit cannabinoid to build up to concentrations that are detectable in drug testing. Choosing broad-spectrum CBD gummies instead is an easy way to avoid this issue entirely. Factors That Affect How Long CBD Gummies Last Let’s take a more detailed look at some of the variables that can impact the duration of effect of CBD gummies and other CBD edibles: Dosage The more CBD you take, the longer it lasts in your system. There’s a certain point where your body simply can’t admit any more CBD, but higher doses of the cannabinoid generally lead to longer effects and half life. Body Chemistry Your individual metabolism and other aspects of your body chemistry impact how long CBD and other substances stay in your system. Consult with your doctor if you’re interested in medical tests that might help you learn more. Food Intake Taking CBD gummies on an empty stomach or avoiding food while their effects last can lead to longer-lasting effects. Eating healthy, high-fiber foods will also reduce the half-life of CBD. Product Quality Oral CBD absorption varies considerably based on the quality of the CBD extract and the other ingredients included in the product. The presence of minor cannabinoids and terpenes can improve CBD absorption, for instance, as can certain encapsulation methods. CBD products lacking contaminants will also last longer and offer effects that are more enjoyable. How Can You Make CBD Gummies Last Longer? The best way to make CBD gummies last longer is to take more of them on an empty stomach. It gets a bit more complicated than that, however, and you might be curious if the duration that CBD gummies last has any impact on their detectability in drug testing: For Effects If you want your CBD gummies to last longer, start by taking a larger dose. The more CBD you take, the longer it will take your body to process it out — up to a point. Increase your dose slowly to avoid digestive discomfort. It can also help to take your CBD gummies on an empty stomach. Not needing to compete with food will speed up CBD’s digestion. It’s also worth noting that taking certain prescription medications will extend the effects of CBD — but their own effects are extended at the same time, leading to potentially dangerous complications. For Detectability For purposes of making sure CBD can’t be detected in your system, you’ll want to start looking at how to make CBD gummies last a briefer amount of time, not longer. But, you don’t have to worry about CBD detectability at all if you choose broad-spectrum CBD gummies, which don’t have any THC to be detected in the first place. How Does This Apply to Daily Use or Testing? Knowing how long CBD gummies last in your system is vital both when developing a daily dose and preparing for upcoming drug testing: Daily Dosing Knowing how long the effects of CBD gummies last is indispensable when developing a reliable daily dose schedule. Understanding that CBD gummies generally wear off within 6 hours maximum, for instance, might prompt you to take them three times per day — morning, noon, and night. Drug Test Prep Understanding the half-life of CBD (around 24 hours) and also recognizing that it’s THC, not CBD, that drug tests detect is vital to preparing for upcoming drug testing. All you really need to know in the end is that avoiding THC by choosing broad-spectrum CBD or CBD isolate gummies solves all your hemp drug testing concerns. Frequently Asked Questions How long do the effects of CBD gummies last? The effects of CBD oil gummies generally last around 3-6 hours with lower doses offering briefer and milder effects. Your body processes CBD at its own rhythm, however, and CBD interacts with certain medications as well. In all, there are quite a few different factors that might impact the duration of effect of CBD oils and edibles under your individual circumstances — consult with your doctor to learn more. How long does CBD from gummies stay in your system? The amount of time that the CBD in gummies lasts in your system depends both on the CBD dosage you choose and your own personal metabolism. If you only take CBD gummies once, they’ll flush out of your system in 1-3 days. Taking CBD gummies on a daily basis, however, will lead to so much CBD accumulating that it might take 30 days to fully excrete. Remember that it’s THC drug tests detect, though, not CBD. Will CBD gummies show up on a drug test? Only full-spectrum CBD gummies have any chance of showing up on a drug test, and that’s only if you take a lot over a short period. Gummies containing broad-spectrum CBD or CBD isolate do not have any potential whatsoever of showing up on a drug test. How long do CBD sleep gummies last? CBD gummies for sleep usually last the same amount of time as other sleep gummies, but their effects might be lengthened somewhat by the presence of melatonin and other natural sleep supplements often also included in CBD sleep gummies. How long do CBD with THC gummies last? CBD gummies that contain THC might last slightly longer due to the synergy between cannabinoids known as the entourage effect. However, it’s unlikely that THC will make CBD gummies last noticeably longer for most users. Conclusion: CBD Gummies & Your Body The cannabis plant is home to many cannabinoids, some of which the federal government still views as illegal. Knowing how to avoid potential drug testing concerns by choosing pure CBD products allows you to consume CBD as nature intended — just as choosing high-quality CBD gummies helps ensure that the CBD effects you’re looking for last their full intended duration. As you embark on your CBD journey, just remember that employers and even government organizations are starting to look more leniently on both CBD and THC use. In the same way, remember that ingesting CBD no longer has to involve THC — choose broad-spectrum, hemp-derived CBD gummies from Colorado Botanicals to experience the clean and pure CBD gummy effects you deserve.

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March 8, 2025

Is CBD Legal in Kansas? Laws, Restrictions, & More

Kansas is no stranger to agriculture, which is perhaps part of why the state has taken such a hands-on approach to regulating its hemp industry. While many states are content to stick with federal law, Kansas has enacted a slew of hemp-related bills designed to limit hemp commerce — sometimes resulting in arrests. Even though Kansas has a contentious relationship with its hemp producers, you should remain unaffected as a hemp user. State governments cannot countermand the US Constitution, which says you can buy CBD products from other states and have them shipped to Kansas. So even if Kansas says certain types of CBD are illegal to buy within its borders, you can still buy them online (technically beyond state lines). Just do remember that Kansas law enforcement has been unusually proactive in arresting individuals suspected of possessing smokable hemp especially. Stay away from any products that look and smell exactly like marijuana, though, and you should be able to enjoy CBD in Kansas exactly as you please — ordered online from Colorado Botanicals for the ultimate convenience. CBD vs. Marijuana The difference between legal hemp and illegal marijuana in Kansas ultimately boils down to the space between two major cannabinoids — THC and CBD. One is considered “marijuana” both by Kansas and at the federal level, and the other is categorized as legal industrial hemp. To understand more, let’s take a look at CBD and THC in greater detail: CBD Cannabidiol (CBD) is a non-intoxicating component of the Cannabis sativa plant. If they contain less than 0.3% THC, CBD products are generally considered “industrial hemp” at the federal level. Though CBD can’t get you high, it has a number of very impressive potential benefits. Is CBD Legal in Kansas? Yes, CBD is legal in Kansas. If CBD products contain less than 0.3% THC, they are legal to both own and use in this state. Buying and selling CBD in Kansas is where things get complicated — overall, it’s easier and safer just to buy your hemp CBD products online. THC THC (delta-9 tetrahydrocannabinol) has powerfully intoxicating effects and is classified as a Schedule I illegal drug at the federal level. It is also illegal in Kansas, which does not have any adult-use or medical cannabis program to speak of. Is Marijuana Legal in Kansas? No, marijuana (THC) is not legal in Kansas. The state has what could be called a medical marijuana program, but it is limited to products with less than 5% THC. Kansas does not have an adult-use cannabis program and is unlikely to adopt one any time soon. What Are the CBD Laws in Kansas? Kansas has adopted a larger number of laws related to CBD and hemp than most other states. Also making Kansas somewhat unique is the punitive and restrictive nature of its hemp laws. Instead of supporting its hemp industry, Kansas has put in place CBD laws that seem intent on hampering its growth. Below, we’ll take a look at all the laws that have affected your ability to buy, use, produce, and sell CBD in Kansas: SB 263: Alternative Crop Research Act (2018) This bill preempted the federal 2018 Farm Bill (not ratified until 2019) and placed Kansas in the running as a state at the forefront of industrial hemp research. Most of this law was superseded by HB 2167 in 2019. SB 282 (2018) SB 282 technically legalized CBD in Kansas, but only CBD products with 0% THC. It’s still the case that CBD products sold in Kansas can’t contain any THC at all, but subsequent laws loosened THC limits for farmers to make growing hemp plants possible. SB 28: Clair and Lola's Law (2019) You could say that SB 28 legalized medical marijuana in Kansas, but to do so would legitimize the most milquetoast medical cannabis legalization effort in American history. Only 5% maximum THC is allowable in Kansas medical marijuana and products, which are only made available to individuals with certain terminal or incurable conditions. HB 2167: Commercial Industrial Hemp Act (2019) Considered the definitive piece of legislation on CBD in Kansas, HB 2167 established licensing requirements for growing, processing and selling hemp, and it famously banned smokable CBD flower. Perhaps most importantly, HB 2167 retained the state’s earlier requirement that CBD products contain 0.0% THC, placing Kansas alone with Idaho as the USA’s most anti-hemp states. Current Restrictions and Kansas CBD Laws In Kansas, it is illegal to sell CBD products containing any THC at all — the state has a 0.0% THC limit. It is also illegal to sell smokable hemp in Kansas (mainly because it always contains at least some THC). Kansas has even taken a somewhat unique approach to enforcing CBD laws by assuming that any products not provable as CBD are instead marijuana. The burden is upon the accused individual to prove their legal CBD products do not contain THC. This has led to a spate of CBD-related arrests in Kansas and the recent raiding of a major CBD store. Residents of Kansas buying CBD products online (even 0% THC broad-spectrum products) are recommended to have CBD orders shipped directly to their homes or to a PO box instead of to an office address. It is also probably best not to travel with CBD products within the state on the off chance a Kansas police officer might mistake your CBD for marijuana. How Old Do I Have to Be to Buy CBD in Kansas? There is no age limit on CBD purchases in Kansas. Despite putting quite a few other restrictions in place, there is no official age you have to be to buy CBD in the state. Most CBD retailers (both in Kansas and online) ask that their customers be at least 18-21 years of age. Can I Buy CBD in Kansas? It’s certainly possible to buy CBD in Kansas, but you’ll have a much easier time with some approaches than others. If you’re looking to buy CBD gummies nearby — or any other type of CBD product, for that matter — your best bet will be shopping online. We’ll take a look at each of your available options below: Online CBD oils, CBD creams, CBD gummies, and all other types of hemp-derived products are easiest to buy in Kansas when you shop online. Colorado Botanicals is the internet’s most certified and respected CBD brand — we’re especially known for our rare cannabinoid collection, including sleep-boosting CBN oils. CBD Stores CBD stores near you in Kansas are very unlikely to carry the CBD products you’re looking for. They’re restricted to zero-THC products, first of all, and every Kansas CBD store owner is rightfully concerned about the possibility of state law enforcement raids. Many Kansas CBD shops have already shuttered their doors, in fact. Dispensaries Kansas does not have any medical or adult-use dispensaries. The state’s “medical marijuana program,” in which patients with terminal conditions can access products with up to 5% THC, is administered directly by licensed physicians. So, it will be impossible to get the CBD products you want this way. Vitamin Stores Supplement shops, natural food stores, and similar establishments are among the most likely places you’ll find CBD products in Kansas. All the same, these stores are limited to carrying 0%-THC products, and they won’t carry a wide selection. Supermarket It’s very unlikely that any supermarkets will carry CBD in Kansas. The state’s conservative politics combine with restrictive legislation to make the pros far outweigh the cons for Kansas supermarket operators and regional buyers. Are CBD Gummies Legal in Kansas? Yes, CBD gummies are legal in Kansas as long as they comply with the state’s overall 0% THC policy. Kansas has not moved specifically to ban or otherwise restrict the sale of edible THC-free CBD products. Is CBN Legal in Kansas? Yes, the hemp cannabinoid cannabinol (CBN) is legal in Kansas as long as products containing it include 0% THC. Kansas has not specifically moved to ban CBN. Frequently Asked Questions Do I need a prescription to buy CBD in Kansas? No, it is not necessary to secure a doctor’s prescription to buy CBD in Kansas. You will need a doctor’s approval to buy any products with more than 0% THC, though. Can I fly to Kansas with CBD? Yes, you can fly to Kansas with CBD in your luggage. The US Constitution’s Commerce Clause protects interstate commerce and travel, and Kansas has not specifically banned CBD imports. Can I vape CBD if I'm 18 in Kansas? You can vape CBD at any age in Kansas. The state has not put any restrictions on CBD vaping. Just remember that CBD products must contain 0% THC to be legal in Kansas. Can I smoke CBD flower in Kansas? No, it is not legal to own or smoke CBD flower in Kansas since this type of CBD product always contains at least some THC. Most of the CBD-related arrests in Kansas have involved CBD flower. Summary: Kansas CBD Laws It’s a good thing for residents of the state that Kansas CBD laws mainly impact the sale and production of the cannabinoid. Thanks to the Constitution, the best CBD products in the country are at your fingertips. Trust Colorado Botanicals to ship top-tier CBD to any address in Kansas. Sources The Washington Times https://www.washingtontimes.com. (2019, November 15). Drug charges dropped against Lawrence CBD store owner. The Washington Times. https://www.washingtontimes.com/news/2019/nov/15/drug-charges-dropped-against-lawrence-cbd-store-ow/ Kansas Legislative Research Department. (2018). Alternative Crop Research Act; SB 263. https://www.kslegislature.gov/li_2018/b2017_18/measures/documents/summary_sb_263_2018.pdf State of Kansas Legislature. (n.d.). SENATE BILL No. 282. In State of Kansas Legislature. https://www.kslegislature.gov/li_2018/b2017_18/measures/documents/sb282_enrolled.pdf Kansas Legislative Research Department. (2019). Claire and Lola’s Law—Possession of certain cannabidiol treatment preparations, actions and proceedings prohibited, affirmative defense; Grandfathering of certain podiatrists; SB 28. https://kslegislature.gov/li_2020/b2019_20/measures/documents/summary_sb_28_2019.pdf Kansas Legislative Research Department. (2019). Commercial Industrial Hemp Program; Senate Sub. for HB 2167. In Kansas Legislative Research Department. https://kslegislature.gov/li_2020/b2019_20/measures/documents/summary_hb_2167_2019.pdf RCPD executes search warrant at CBD American Shaman in Manhattan; Arrest made. (n.d.). Riley County Police Department, KS. https://www.rileycountypolice.org/CivicAlerts.aspx?AID=654

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March 5, 2025

Can CBD Make You More Anxious? The Hidden Risks

CBD usually has a decidedly relaxing effect that often soothes anxiety. In rare cases, though, CBD can heighten existing anxiety or make you feel anxious when you weren’t before. Almost always, CBD isn’t to blame — rather, it’s another cannabinoid’s effects at play, a dosage problem, or interaction with prescription medication. In this guide, learn why CBD might cause you to feel anxious, and find out what to do when CBD-related anxiety strikes. The goal is to avoid the simple mistakes that can turn taking CBD from relaxing relief into uncomfortable anxiety. As you’ll see, picking the right CBD product makes a huge difference — trust Colorado Botanicals for high-purity, thoughtfully formulated CBD that won’t make you anxious. What CBD Does in the Body Most cannabinoids interact with neuroreceptors in the human body that are almost eerily compatible with cannabis — called cannabinoid receptors, CB1 and CB2 are primarily responsible for the intoxicating and pain-relieving effects of THC and similarly structured cannabis compounds. CBD doesn’t interact with CB1 or CB2, however. Instead, it primarily acts on your vanilloid and serotonergic systems — the latter of which is critically involved in mood, stress, and anxiety. Serotonin is one of the primary targets of conventional anxiety therapies, so any plant-derived substance that interacts strongly with your serotonergic system will naturally be of great interest to the medical science community. What’s truly remarkable about CBD is its usual lack of significant side effects. Any substance that changes the behavior of your serotonergic system, however, runs at least some risk of causing unintended disruption. And, beyond CBD’s inherent mild risks among sensitive individuals, there are also product preparation and usage issues that must be managed to ensure CBD reduces anxiety as intended. Why Might CBD Cause Anxiety If taking CBD has resulted in an increase rather than a decrease in anxiety symptoms, a few different variables could be at play: Incorrect CBD Dosage It’s best to get used to the effects of CBD gradually. Especially in the case of full-spectrum CBD, choosing the incorrect CBD dosage can cause unwanted anxiety in individuals who aren’t used to taking hemp oil. Full-spectrum CBD can contain up to 0.3% THC, so especially when taken in high dosage, products containing this type of CBD have the potential to exacerbate anxiety symptoms. THC Content in CBD Products If you think that 0.3% isn’t very much, you’re right. For some people, though, even a third of a percent of THC can be enough to trigger subtle but very real anxiety symptoms. That’s why it’s so convenient you can get CBD gummies and other CBD products in broad-spectrum — the same as full-spectrum CBD, but without any THC. Individual Sensitivity to CBD Even without the presence of any THC at all, it’s still the case that some individuals are sensitive to CBD. Cannabinoid hyperemesis syndrome (CHS) is a very rare condition, but for most affected individuals, all cannabinoids — not just THC — trigger symptoms. So, either CHS or some other personal condition could predispose certain individuals to have intolerance issues with CBD. Consult with your doctor to learn more. Interaction with Other Substances CBD competes with many prescription medications for liver enzymes used to process substances out of the digestive tract. If there aren’t enough of these enzymes present, both CBD and any prescription drugs you’re taking can stay in your system longer than intended. This isn’t usually a problem for CBD, but some prescription drugs make you anxious if they aren’t flushed out quickly. Or, they can accumulate in dangerous doses if they aren’t processed normally. If you’re already using prescription medications for anxiety or any other condition, consult with your doctor before you start using CBD. Poor Product Quality It wouldn’t be thorough if we neglected mentioning that some CBD products are simply low-quality. In the case of contaminated or bottom-tier products, it might not be CBD at all that’s causing you to become more anxious. Investigate the ingredients in any CBD products you’ve used as you hunt down the source of your increased anxiety symptoms. Don’t be afraid to get into the lab reports and check toxin levels — certain agrochemicals have been linked to increases in anxiety. Can CBD Make You More Anxious? Under rare circumstances, yes — CBD can make you more anxious. CBD usually reduces anxiety symptoms (if it affects them at all), but contaminated CBD products, using the wrong type of CBD, and personal predispositions toward cannabis compounds can all play a role here. If using CBD leads to an increase in your anxiety symptoms, stop using the CBD product that caused these symptoms immediately, and consult with your doctor as soon as possible. CBD should not cause anxiety Product contamination, trace THC, and medical conditions can impact CBD’s effects Increased anxiety is one potential consequence Also consider the potential role of prescription medication interactions Seek medical attention if CBD causes anxiety How to Avoid Panic Attacks with CBD The best way to avoid panic attacks by using CBD is to keep your favorite CBD product on hand at all times (high-dose 25mg CBD gummies are great for this purpose), and simply take a dose of hemp whenever you feel anxiety symptoms coming on. Even better, take CBD preemptively before you encounter a scenario that might make you anxious or even full-on panicked. Post-traumatic stress disorder (PTSD) and related mental health conditions can make debilitating panic attacks into everyday occurrences. The cannabis plant has given us a powerful ally in CBD, however, which provides gentle and subtle relief that doesn’t get in the way of your daily activities — well, it can make you a little sleepy. What to Do If CBD Makes You Anxious Here’s how to not panic if taking CBD makes you more instead of less anxious: Remember CBD doesn’t last that long. The effects of orally ingested CBD pass their peak after around an hour. Understand it probably wasn’t CBD. An additional ingredient or drug interaction was most likely to blame. Recognize that CBD is natural and gentle. This isn’t just medical cannabis — mainstream clinical trials support using CBD for anxiety. Ask for help. Any adverse effects of CBD will usually pass quickly, but calling a friend or your doctor might provide the supporting hand you need. Frequently Asked Questions Does CBD make anxiety worse? Taking CBD can sometimes worsen anxiety disorders, but CBD itself isn’t often to blame. Instead, it’s an interaction with other medications, contaminants in the CBD product, or some other factor that’s causing your anxiety symptoms to get worse. If you’re concerned that CBD is worsening your anxiety, stop using the product immediately, investigate its ingredients, and consult with your doctor. Can CBD make you paranoid? As a substance used to treat anxiety, CBD generally doesn’t make you more paranoid. It’s unlike THC in this way — while adverse effects similar to panic disorder are often noted at high doses of THC, CBD is known to reduce anxiety symptoms, even those caused by THC. Can CBD gummies make me anxious? Taking CBD gummies for anxiety or stress can sometimes have the opposite effect of what you intended — but it’s usually the gummies that are to blame. Unless you have a rare cannabis allergy or you’re especially sensitive to the small amounts of THC in full-spectrum CBD, gummies containing CBD shouldn’t make you anxious. Try using a THC-free CBD product, and consult with a doctor if anxiety symptoms persist. Can Full Spectrum CBD make anxiety worse? Out of all the different types of CBD, full-spectrum CBD is the most likely to worsen your anxiety symptoms. Adverse reactions are less likely with broad-spectrum CBD, which does not contain any THC at all. Is CBD good for anxiety? Most people who have used CBD would likely say it’s good for anxiety. Medical scientists haven’t reached a conclusion on the usefulness of CBD for anxiety yet, though. What’s apparent is that adverse reactions to CBD are rare, and CBD is much more likely to help with your anxiety than worsen it. Conclusion If the CBD product you bought for anxiety isn’t working how you planned, don’t give up on CBD just yet. Ask your doctor for an expert analysis of the situation, and consider all the factors we’ve discussed: The quality of the product Full-spectrum vs. other types of CBD Individual predispositions toward cannabinoids Interactions with prescription medications Choosing the wrong CBD dose Some situations might make it dangerous to continue using CBD oil. If your doctor thinks it’s safe, however, try experimenting with different CBD types. If full-spectrum CBD oil made you anxious, for instance, why not try carefully calibrated CBD mood gummies next instead? Whether you’re standing up against Generalized Anxiety Disorder (GAD) or any other type of anxiety, CBD can be an excellent tool in your battle. Keep fighting the good fight, and remember that countless people with even treatment-resistant anxiety disorders have found unexpected relief in CBD. Sources Muller, C., Morales, P., & Reggio, P. H. (2019). Cannabinoid ligands targeting TRP channels. Frontiers in Molecular Neuroscience, 11. https://doi.org/10.3389/fnmol.2018.00487 De Gregorio, D., McLaughlin, R. J., Posa, L., Ochoa-Sanchez, R., Enns, J., Lopez-Canul, M., Aboud, M., Maione, S., Comai, S., & Gobbi, G. (2018). Cannabidiol modulates serotonergic transmission and reverses both allodynia and anxiety-like behavior in a model of neuropathic pain. Pain, 160(1), 136–150. https://doi.org/10.1097/j.pain.0000000000001386 Glyphosate increases anxiety-like behaviors in rat model, expert says. (n.d.). National Institute of Environmental Health Sciences. https://factor.niehs.nih.gov/2023/11/science-highlights/anxiety-like-behavior-in-rat-model Dahlgren, M. K., Lambros, A. M., Smith, R. T., Sagar, K. A., El-Abboud, C., & Gruber, S. A. (2022). Clinical and cognitive improvement following full-spectrum, high-cannabidiol treatment for anxiety: open-label data from a two-stage, phase 2 clinical trial. Communications Medicine, 2(1). https://doi.org/10.1038/s43856-022-00202-8 Zuardi, A. W., Shirakawa, I., Finkelfarb, E., & Karniol, I. G. (1982). Action of cannabidiol on the anxiety and other effects produced by ?9-THC in normal subjects. Psychopharmacology, 76(3), 245–250. https://doi.org/10.1007/bf00432554

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